Anticholinergics and Antimuscarinics: these drugs slow down the contractions of the bladder wall, relaxing the bladder and decreasing the need to urinate. Commonly prescribed anticholinergics include:
· Oxybutynin (also available as a transdermal patch)
· Trospium Chloride (Regurin, Regurin XL)
· Solifenacin succinate (Vesicare)
· Fesoterodine fumerate (Toviaz)
Mirabegron is a once-daily, beta-3 adrenoceptor agonist for the symptomatic treatment of urgency, frequency and/or urgency incontinence. It works by stimulating the beta-3 receptors in the muscle of the bladder causing relaxation of the bladder muscle and improving storage capacity without impeding voiding.
Vesomni (a combination drug containing solifenacin succinate and tamsulosin hydrochloride)
Vesomni is used in men to treat both storage and voiding symptoms which are caused by bladder problems and benign prostate enlargement.
Alpha Blockers: These are medications which relax the muscles of the prostate and improve urinary flow. Commonly prescribed alpha-blockers are:
· Doxazosin mesylate
· Terazosin HCI
· Prazosin HCI
· Tamsulosin hydrochloride
Desmopressin: This can be used to reduce urine output from the kidneys and thus reduce the amount of times you need to urinate during the night. This medication must be prescribed by a doctor.
Tri-Cyclic Anti-Depressants: These are sometimes used to treat urge incontinence and may be useful because of their ability to slow down the contractions of the bladder smooth muscles. Commonly prescribed tricyclics are: